Frontiers in the search for new antimicrobials: new perspectives

نویسندگان

چکیده

Infections caused by bacteria and fungi resistant to antimicrobials are one of the main public health problems in world. These microorganisms associated with high rates morbidity mortality also hospital costs. Their emergence spread closely related excessive inappropriate use medical veterinary practices animal production. For treatment Candida spp. there few classes antifungals available for treatment, being: azole derivatives, polyenes echinocandins. The class azoles includes imidazole derivatives (ketoconazole, miconazole, clotrimazole), triazole (fluconazole, itraconazole voriconazole) posaconazole. drugs can be used topical us as well prophylaxis invasive infections. wide these has led a strong selection strains them, which is increasingly growing. need produce new antimicrobial requires different strategies, among we highlight importance bioprospecting secondary metabolites environmental potential activity.

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ژورنال

عنوان ژورنال: Brazilian Journal of Development

سال: 2023

ISSN: ['2525-8761']

DOI: https://doi.org/10.34117/bjdv9n6-148